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1 keywords

CATH Domain 3kfcC00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

P55055
NR1H2_HUMAN
Homo sapiens
Oxysterols receptor LXR-beta

PDB Structure

PDB 3KFC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists.
Bernotas, R.C., Singhaus, R.R., Kaufman, D.H., Travins, J.M., Ullrich, J.W., Unwalla, R., Quinet, E., Evans, M., Nambi, P., Olland, A., Kauppi, B., Wilhelmsson, A., Goos-Nilsson, A., Wrobel, J.
Bioorg.Med.Chem.Lett.
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