CATH Domain 3k2iA01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.2240	Acyl-CoA thioester hydrolase/BAAT N-terminal domain

Domain Context

CATH Clusters

Superfamily	Acyl-CoA thioester hydrolase/BAAT N-terminal domain
Functional Family	acyl-coenzyme A thioesterase 4

Enzyme Information

3.1.2.2	Palmitoyl-CoA hydrolase. based on mapping to UniProt Q8N9L9 Palmitoyl-CoA + H(2)O = CoA + palmitate. -!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
3.1.2.3	Succinyl-CoA hydrolase. based on mapping to UniProt Q8N9L9 Succinyl-CoA + H(2)O = CoA + succinate.

UniProtKB Entries (1)

ACOT4_HUMAN

Homo sapiens

Peroxisomal succinyl-coenzyme A thioesterase

PDB Structure

PDB	3K2I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human Acyl-coenzyme A thioesterase 4 Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H. To be Published