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1 keywords

CATH Domain 3jz6B01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.470 D-amino Acid Aminotransferase; Chain A, domain 1
Homologous Superfamily 3.30.470.10 Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain

Domain Context

CATH Clusters

Superfamily 3.30.470.10
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt A0R066
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

A0R066
ILVE_MYCS2
Mycolicibacterium smegmatis MC2 155
Branched-chain-amino-acid aminotransferase

PDB Structure

PDB 3JZ6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.
Castell, A., Mille, C., Unge, T.
Acta Crystallogr.,Sect.D
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