CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.238.260
Functional Family Homocitrate synthase, mitochondrial

Enzyme Information

2.3.3.14
Homocitrate synthase.
based on mapping to UniProt Q9Y823
Acetyl-CoA + H(2)O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4- tricarboxylate + CoA.
-!- Belongs in the alpha-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36. -!- Also acts with oxaloacetate as substrate, but more slowly. -!- Formerly EC 4.1.3.21.

UniProtKB Entries (1)

Q9Y823
HOSM_SCHPO
Schizosaccharomyces pombe 972h-
Homocitrate synthase, mitochondrial

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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