CATH Domain 3ht3A04

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	DNA polymerase I

Enzyme Information

UniProtKB Entries (1)

D9N168_GEOSE

Geobacillus stearothermophilus

DNA polymerase I

PDB Structure

PDB	3HT3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. Wu, E.Y., Beese, L.S. J.Biol.Chem.