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1 keywords

CATH Domain 3h4tA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2000 Glycogen Phosphorylase B;

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Sterol 3-beta-glucosyltransferase UGT80A2

Enzyme Information

2.4.1.311
dTDP-epi-vancosaminyltransferase.
based on mapping to UniProt P96558
dTDP-beta-L-4-epi-vancosamine + devancoaminyl-vancomycin = dTDP + chloroorienticin B.
-!- The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin.

UniProtKB Entries (2)

Q6ZZJ7
Q6ZZJ7_ACTTI
Actinoplanes teichomyceticus
Glycosyltransferase
P96558
GTFA_AMYOR
Amycolatopsis orientalis
DTDP-epi-vancosaminyltransferase

PDB Structure

PDB 3H4T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Chimeric glycosyltransferases for the generation of hybrid glycopeptides
Truman, A.W., Dias, M.V.B., Wu, S., Blundell, T.L., Huang, F., Spencer, J.B.
Chem.Biol.
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