CATH Domain 3fcxB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	S-formylglutathione hydrolase

Enzyme Information

3.1.2.12	S-formylglutathione hydrolase. based on mapping to UniProt P10768 S-formylglutathione + H(2)O = glutathione + formate. -!- Also hydrolyzes S-acetylglutathione, more slowly.
3.1.1.56	Methylumbelliferyl-acetate deacetylase. based on mapping to UniProt P10768 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate. -!- Acts on short-chain acyl esters of 4-methylumbelliferone, but not on naphthyl, indoxyl or thiocholine esters.

UniProtKB Entries (1)

ESTD_HUMAN

Homo sapiens

S-formylglutathione hydrolase

PDB Structure

PDB	3FCX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of human esterase D: a potential genetic marker of retinoblastoma Wu, D., Li, Y., Song, G., Zhang, D., Shaw, N., Liu, Z.J. Faseb J.