CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.520 | Peroxidase; domain 1 |
|
1.10.520.10 |
Domain Context
CATH Clusters
| Superfamily | 1.10.520.10 |
| Functional Family | Cytochrome c peroxidase |
Enzyme Information
| 1.11.1.5 |
Cytochrome-c peroxidase.
based on mapping to UniProt P00431
2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O.
|
| 1.11.1.11 |
L-ascorbate peroxidase.
based on mapping to UniProt P48534
2 L-ascorbate + H(2)O(2) + 2 H(+) = L-ascorbate + L-dehydroascorbate + 2 H(2)O.
-!- Oxidizes ascorbate and low molecular weight aromatic substrates. -!- The monodehydroascorbate radical produced is either directly reduced back to ascorbate by EC 1.6.5.4 or undergoes non-enzymatic disproportionation to ascorbate and dehydroascorbate.
|
UniProtKB Entries (2)
| P48534 |
APX1_PEA
Pisum sativum
L-ascorbate peroxidase, cytosolic
|
| P00431 |
CCPR_YEAST
Saccharomyces cerevisiae S288C
Cytochrome c peroxidase, mitochondrial
|
PDB Structure
| PDB | 3E2N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Engineering ascorbate peroxidase activity into cytochrome c peroxidase.
Biochemistry
|
