CATH Domain 3drmA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Serine protease inhibitor

Enzyme Information

UniProtKB Entries (1)

A1AT_HUMAN

Homo sapiens

Alpha-1-antitrypsin

PDB Structure

PDB	3DRM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. Gooptu, B., Miranda, E., Nobeli, I., Mallya, M., Purkiss, A., Brown, S.C., Summers, C., Phillips, R.L., Lomas, D.A., Barrett, T.E. J.Mol.Biol.