CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.245 | Lipoxygenase-1; domain 5 |
|
1.20.245.10 | Lipoxygenase-1; Domain 5 |
Domain Context
CATH Clusters
| Superfamily | Lipoxygenase-1; Domain 5 |
| Functional Family | Arachidonate 5-lipoxygenase a |
Enzyme Information
| 3.3.2.- |
Ether hydrolases.
based on mapping to UniProt P18054
|
| 1.13.11.31 |
Arachidonate 12-lipoxygenase.
based on mapping to UniProt P18054
Arachidonate + O(2) = (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa- 5,8,10,14-tetraenoate.
-!- The product is rapidly reduced to the corresponding 12S-hydroxy compound.
|
UniProtKB Entries (1)
| P18054 |
LOX12_HUMAN
Homo sapiens
Arachidonate 12-lipoxygenase, 12S-type
|
PDB Structure
| PDB | |
| External Links | |
| Method | |
| Organism | |
| Primary Citation |
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