CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.20 | Single Sheet |
|
2.20.130 | S-adenosyl-L-methionine-dependent methyltransferases |
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2.20.130.10 | CAC2371-like domains |
Domain Context
CATH Clusters
| Superfamily | CAC2371-like domains |
| Functional Family | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose |
Enzyme Information
| 2.1.1.234 |
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase.
based on mapping to UniProt Q9ZGH6
2 S-adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D- glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,4,6- trideoxy-alpha-D-glucopyranose.
-!- The enzyme is involved in the biosynthesis of desosamine, a 3-(dimethylamino)-3,4,6-trideoxyhexose found in certain macrolide antibiotics such as erthyromycin, azithromycin, and clarithromycin.
|
UniProtKB Entries (1)
| Q9ZGH6 |
DESVI_STRVZ
Streptomyces venezuelae
DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose
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PDB Structure
| PDB | |
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| Method | |
| Organism | |
| Primary Citation |
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