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CATH Classification

Domain Context

CATH Clusters

Superfamily Transcription Factor, Ets-1
Functional Family Connector enhancer of kinase suppressor of Ras 2

Enzyme Information

UniProtKB Entries (2)

Q8WXI2
CNKR2_HUMAN
Homo sapiens
Connector enhancer of kinase suppressor of ras 2
Q8ML92
AVE_DROME
Drosophila melanogaster
Protein aveugle

PDB Structure

PDB 3BS5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Rajakulendran, T., Sahmi, M., Kurinov, I., Tyers, M., Therrien, M., Sicheri, F.
Proc.Natl.Acad.Sci.USA
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