×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Proprotein convertase subtilisin/kexin type 9
Functional Family Proprotein convertase subtilisin/kexin type 9

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q8NBP7

UniProtKB Entries (1)

Q8NBP7
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9

PDB Structure

PDB 3BPS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Molecular basis for LDL receptor recognition by PCSK9.
Kwon, H.J., Lagace, T.A., McNutt, M.C., Horton, J.D., Deisenhofer, J.
Proc.Natl.Acad.Sci.Usa
CATH-Gene3D is a Global Biodata Core Resource Learn more...