CATH Domain 3bo5A00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.270	Beta-clip-like
	2.170.270.10	SET domain

Domain Context

CATH Clusters

Superfamily	SET domain
Functional Family	Histone-lysine N-methyltransferase SETMAR

Enzyme Information

2.1.1.43	Histone-lysine N-methyltransferase. based on mapping to UniProt Q53H47 S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
3.1.-.-	Acting on ester bonds. based on mapping to UniProt Q53H47

UniProtKB Entries (1)

SETMR_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETMAR

PDB Structure

PDB	3BO5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The Crystal Structure of Methyltransferase Domain of Human Histone-lysine N-methyltransferase SETMAR in Complex With AdoHcy. Wu, H., Lunin, V.V., Ren, H., Dobrovetsky, E., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Plotnikov, A.N. To be Published