CATH Domain 3bg4C00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Chymotrypsinogen A

Enzyme Information

3.4.21.1

Chymotrypsin.

based on mapping to UniProt P00766

Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.

UniProtKB Entries (2)

P46443	GUAM_HIRNI Hirudo nipponia Guamerin
P00766	CTRA_BOVIN Bos taurus Chymotrypsinogen A

PDB Structure

PDB	3BG4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The crystal structure of guamerin in complex with chymotrypsin and the development of an elastase-specific inhibitor. Kim, H., Chu, T.T.T., Kim, D.Y., Kim, D.R., Nguyen, C.M.T., Choi, J., Lee, J.R., Hahn, M.J., Kim, K.K. J.Mol.Biol.