CATH Domain 3awiF03

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.9	D-Amino Acid Oxidase; Chain A, domain 2
	3.30.9.10	D-Amino Acid Oxidase, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	D-Amino Acid Oxidase, subunit A, domain 2
Functional Family	tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC

Enzyme Information

2.1.1.61	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase. based on mapping to UniProt P77182 S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2- thiouridylate. -!- Specific for the terminal methyl group of 5-methylaminomethyl-2- thiouridylate.
1.5.-.-	Acting on the CH-NH group of donors. based on mapping to UniProt P77182

UniProtKB Entries (1)

MNMC_ECOLI

Escherichia coli K-12

TRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC

PDB Structure

PDB	3AWI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli Kitamura, A., Sengoku, T., Nishimoto, M., Yokoyama, S., Bessho, Y. Protein Sci.