CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.360 | Flavodoxin domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.360 |
| Functional Family | FMN-dependent NADH-azoreductase |
Enzyme Information
| 1.7.1.17 |
FMN-dependent NADH-azoreductase.
based on mapping to UniProt P41407
Anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH.
-!- The enzyme catalyzes the reductive cleavage of an azo bond in aromatic azo compounds to form the corresponding amines. -!- Does not accept NADPH. -!- Cf. EC 1.7.1.6.
|
UniProtKB Entries (1)
| P41407 |
AZOR_ECOLI
Escherichia coli K-12
FMN-dependent NADH-azoreductase
|
PDB Structure
| PDB | 2Z9D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Expansion of Substrate Specificity and Catalytic Mechanism of Azoreductase by X-ray Crystallography and Site-directed Mutagenesis
J.Biol.Chem.
|
