CATH Domain 2z5vA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10140	Toll/interleukin-1 receptor homology (TIR) domain

Domain Context

CATH Clusters

Superfamily	Toll/interleukin-1 receptor homology (TIR) domain
Functional Family	Myeloid differentiation primary response protein MyD88

Enzyme Information

UniProtKB Entries (1)

MYD88_HUMAN

Homo sapiens

Myeloid differentiation primary response protein MyD88

PDB Structure

PDB	2Z5V
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Ohnishi, H., Tochio, H., Kato, Z., Orii, K.E., Li, A., Kimura, T., Hiroaki, H., Kondo, N., Shirakawa, M. Proc.Natl.Acad.Sci.USA