CATH Domain 2yfoA03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1180	Golgi alpha-mannosidase II

Domain Context

CATH Clusters

Superfamily	Golgi alpha-mannosidase II
Functional Family	Adenylyl-sulfate kinase

Enzyme Information

2.7.-.-	Transferring phosphorus-containing groups. based on mapping to UniProt G4T4R7
3.2.1.22	Alpha-galactosidase. based on mapping to UniProt G4T4R7 Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. -!- Also hydrolyzes alpha-D-fucosides.

UniProtKB Entries (1)

AGASK_RUMGN

[Ruminococcus] gnavus

Bifunctional alpha-galactosidase/sucrose kinase AgaSK

PDB Structure

PDB	2YFO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities Bruel, L., Sulzenbacher, G., Tison-Cervera, M., Pujol, A., Nicoletti, C., Perrier, J., Galinier, A., Ropartz, D., Fons, M., Pompeo, F., Giardina, T. J.Biol.Chem.