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1 keywords

CATH Domain 2wtxD01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2000 Glycogen Phosphorylase B;

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Trehalose-6-phosphate synthase

Enzyme Information

2.4.1.15
Alpha,alpha-trehalose-phosphate synthase (UDP-forming).
based on mapping to UniProt P31677
UDP-alpha-D-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
-!- See also EC 2.4.1.36.

UniProtKB Entries (1)

P31677
OTSA_ECOLI
Escherichia coli K-12
Trehalose-6-phosphate synthase

PDB Structure

PDB 2WTX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors.
Errey, J.C., Lee, S.S., Gibson, R.P., Martinez Fleites, C., Barry, C.S., Jung, P.M.J., O'Sullivan, A.C., Davis, B.G., Davies, G.J.
Angew.Chem.Int.Ed.Engl.
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