CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1160 | Carbamate kinase |
|
3.40.1160.10 | Acetylglutamate kinase-like |
Domain Context
CATH Clusters
| Superfamily | Acetylglutamate kinase-like |
| Functional Family | Carbamate kinase |
Enzyme Information
| 2.7.2.2 |
Carbamate kinase.
based on mapping to UniProt P0A2X7
ATP + NH(3) + hydrogen carbonate = ADP + carbamoyl phosphate + H(2)O.
-!- The enzyme catalyzes the reversible conversion of carbamoyl phosphate and ADP to ATP and carbamate, which hydrolyzes to ammonia and hydrogen carbonate. -!- The physiological role of the enzyme is to generate ATP.
|
UniProtKB Entries (1)
| P0A2X7 |
ARCC1_ENTFA
Enterococcus faecalis V583
Carbamate kinase 1
|
PDB Structure
| PDB | 2WE4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site-Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria.
J.Mol.Biol.
|
