CATH Domain 2w97B00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.760	RNA Cap, Translation Initiation Factor Eif4e
	3.30.760.10	RNA Cap, Translation Initiation Factor Eif4e

Domain Context

CATH Clusters

Superfamily	RNA Cap, Translation Initiation Factor Eif4e
Functional Family	Eukaryotic translation initiation factor 4E

Enzyme Information

UniProtKB Entries (1)

IF4G1_HUMAN

Homo sapiens

Eukaryotic translation initiation factor 4 gamma 1

PDB Structure

PDB	2W97
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site. Brown, C.J., Verma, C.S., Walkinshaw, M.D., Lane, D.P. Cell Cycle