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1 keywords

CATH Domain 2w2iC00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.650 Cupin

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4D

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt B2RXH2

UniProtKB Entries (1)

B2RXH2
KDM4E_HUMAN
Homo sapiens
Lysine-specific demethylase 4E

PDB Structure

PDB 2W2I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family.
Hillringhaus, L., Yue, W.W., Rose, N.R., Ng, S.S., Gileadi, C., Loenarz, C., Bello, S.H., Bray, J.E., Schofield, C.J., Oppermann, U.
J.Biol.Chem.
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