CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1180 | Undecaprenyl pyrophosphate synthetase |
|
3.40.1180.10 | Decaprenyl diphosphate synthase-like |
Domain Context
CATH Clusters
| Superfamily | Decaprenyl diphosphate synthase-like |
| Functional Family | Isoprenyl transferase 2 |
Enzyme Information
| 2.5.1.68 |
(2Z,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt P9WFF5
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)- farnesyl diphosphate.
-!- The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan. -!- Neryl diphosphate can also act as substrate.
|
UniProtKB Entries (1)
| P9WFF5 |
ZFPP_MYCTU
Mycobacterium tuberculosis H37Rv
(2Z,6E)-farnesyl diphosphate synthase
|
PDB Structure
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| Organism | |
| Primary Citation |
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