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1 keywords

CATH Domain 2vavK00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetyl-CoA--deacetylcephalosporin C acetyltransferase

Enzyme Information

2.3.1.175
Deacetylcephalosporin-C acetyltransferase.
based on mapping to UniProt P39058
Acetyl-CoA + deacetylcephalosporin C = CoA + cephalosporin C.
-!- This enzyme catalyzes the final step in the biosynthesis of cephalosporin C.

UniProtKB Entries (1)

P39058
CEFG_ACRCH
Acremonium chrysogenum
Acetyl-CoA--deacetylcephalosporin C acetyltransferase

PDB Structure

PDB 2VAV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The last step in cephalosporin C formation revealed: crystal structures of deacetylcephalosporin C acetyltransferase from Acremonium chrysogenum in complexes with reaction intermediates.
Lejon, S., Ellis, J., Valegard, K.
J. Mol. Biol.
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