CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1190 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase |
|
3.40.1190.20 | Ribokinase |
Domain Context
CATH Clusters
| Superfamily | 3.40.1190.20 |
| Functional Family | 2-dehydro-3-deoxygluconokinase |
Enzyme Information
| 2.7.1.178 |
2-dehydro-3-deoxyglucono/galactono-kinase.
based on mapping to UniProt Q97U29
(1) ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 2-dehydro-3-deoxy-6- phospho-D-gluconate. (2) ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-6- phospho-D-galactonate.
-!- The enzyme from the archaeon Sulfolobus solfataricus is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. -!- It phosphorylates 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3- deoxy-D-galactonate with similar catalytic efficiency. -!- Cf. EC 2.7.1.45 and EC 2.7.1.58.
|
UniProtKB Entries (1)
| Q97U29 |
KDGK_SACS2
Saccharolobus solfataricus P2
2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase
|
PDB Structure
| PDB | 2VAR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Structure of Sulfolobus Solfataricus 2-Keto-3-Deoxygluconate Kinase.
Acta Crystallogr.,Sect.D
|
