CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.2510
Functional Family tRNA pseudouridine synthase Pus10

Enzyme Information

5.4.99.25
tRNA pseudouridine(55) synthase.
based on mapping to UniProt Q3MIT2
tRNA uridine(55) = tRNA pseudouridine(55).
-!- Pseudourine synthase TruB from Escherichia coli specifically modifies uridine(55) in tRNA molecules. -!- The bifunctional archaeal enzyme also catalyzes the pseudouridylation of uridine(54). -!- It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in E.coli tRNAs by thymine.

UniProtKB Entries (1)

Q3MIT2
PUS10_HUMAN
Homo sapiens
Putative tRNA pseudouridine synthase Pus10

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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