CATH Domain 2sgpE02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.81

Streptogrisin B.

based on mapping to UniProt P00777

Hydrolysis of proteins with trypsin-like specificity.

-!- Belongs to peptidase family S1E.

UniProtKB Entries (2)

P68390	IOVO_MELGA Meleagris gallopavo Ovomucoid
P00777	PRTB_STRGR Streptomyces griseus Streptogrisin-B

PDB Structure

PDB	2SGP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I Bateman, K.S., Huang, K., Anderson, S., Lu, W., Qasim, M.A., Laskowski Jr., M., James, M.N. J.Mol.Biol.