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1 keywords

CATH Domain 2r3aA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H5I1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9H5I1
SUV92_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SUV39H2

PDB Structure

PDB 2R3A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural biology of human H3K9 methyltransferases
Wu, H., Min, J., Lunin, V.V., Antoshenko, T., Dombrovski, L., Zeng, H., Allali-Hassani, A., Campagna-Slater, V., Vedadi, M., Arrowsmith, C.H., Plotnikov, A.N., Schapira, M.
Plos One
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