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1 keywords

CATH Domain 2pnqB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.60 4-Layer Sandwich
Topology 3.60.40 Phosphatase 2c; domain 1
Homologous Superfamily 3.60.40.10 PPM-type phosphatase domain

Domain Context

CATH Clusters

Superfamily PPM-type phosphatase domain
Functional Family Pyruvate dehyrogenase phosphatase catalytic subunit 1

Enzyme Information

3.1.3.43
[Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
based on mapping to UniProt O88483
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.
-!- A mitochondrial enzyme associated with EC 1.2.4.1 in the pyruvate dehydrogenase complex.

UniProtKB Entries (1)

O88483
PDP1_RAT
Rattus norvegicus
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

PDB Structure

PDB 2PNQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications.
Vassylyev, D.G., Symersky, J.
J.Mol.Biol.
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