CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.348
(3R)-2'-hydroxyisoflavanone reductase.
based on mapping to UniProt Q40316
A (4R)-4,2'-dihydroxyisoflavan + NADP(+) = a (3R)-2'-hydroxyisoflavanone + NADPH.
-!- This plant enzyme participates in the biosynthesis of the pterocarpan phytoalexins medicarpin, maackiain, and several forms of glyceollin. -!- The enzyme has a strict stereo specificity for the 3R-isoflavanones. -!- Formerly EC 1.1.1.246.

UniProtKB Entries (1)

Q40316
VESTR_MEDSA
Medicago sativa
Vestitone reductase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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