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1 keywords

CATH Domain 2oqpA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.1250 Growth Hormone; Chain: A;
Homologous Superfamily 1.20.1250.70 Interleukin-15/Interleukin-21

Domain Context

CATH Clusters

Superfamily Interleukin-15/Interleukin-21
Functional Family Interleukin

Enzyme Information

UniProtKB Entries (1)

Q9HBE4
IL21_HUMAN
Homo sapiens
Interleukin-21

PDB Structure

PDB 2OQP
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogue.
Bondensgaard, K., Breinholt, J., Madsen, D., Omkvist, D.H., Kang, L., Worsaae, A., Becker, P., Schiodt, C.B., Hjorth, S.A.
J.Biol.Chem.
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