CATH Domain 2op9B03

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1840	main proteinase (3clpro) structure, domain 3
	1.10.1840.10	main proteinase (3clpro) structure, domain 3

Domain Context

CATH Clusters

Superfamily	main proteinase (3clpro) structure, domain 3
Functional Family	Replicase polyprotein 1a

Enzyme Information

UniProtKB Entries (1)

Q6T1E9_CVHSA

SARS coronavirus CUHK-L2

Orf1ab polyprotein

PDB Structure

PDB	2OP9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus. Goetz, D.H., Choe, Y., Hansell, E., Chen, Y.T., McDowell, M., Jonsson, C.B., Roush, W.R., McKerrow, J., Craik, C.S. Biochemistry