CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.11660 | Glycosyl transferase family 10, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Glycosyl transferase family 10, C-terminal domain |
| Functional Family |
Enzyme Information
| 2.4.1.152 |
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase.
based on mapping to UniProt O30511
GDP-beta-L-fucose + (1->4)-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R = GDP + (1->4)-beta-D-galactosyl-(alpha-(1->3)-L-fucosyl)-N-acetyl-D- glucosaminyl-R.
-!- Normally acts on a glycoconjugate where R (see CA line) is a glycoprotein or glycolipid. -!- This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
|
UniProtKB Entries (1)
| O30511 |
FUCT_HELPX
Helicobacter pylori
Alpha-(1,3)-fucosyltransferase FucT
|
PDB Structure
| PDB | |
| External Links | |
| Method | |
| Organism | |
| Primary Citation |
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