CATH Domain 2l2bA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.270	Mutm (Fpg) Protein; Chain: A, domain 2
	2.60.270.20	Cytolysin/lectin

Domain Context

CATH Clusters

Superfamily	Cytolysin/lectin
Functional Family	DELTA-actitoxin-Afr1a

Enzyme Information

UniProtKB Entries (1)

ACTP2_STIHL

Stichodactyla helianthus

DELTA-stichotoxin-She4b

PDB Structure

PDB	2L2B
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicity. Pardo-Cea, M.A., Castrillo, I., Alegre-Cebollada, J., Martinez-Del-Pozo, A., Gavilanes, J.G., Bruix, M. Febs J.