CATH Domain 2l27A00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.1240	Hormone receptor fold
	4.10.1240.10	GPCR, family 2, extracellular hormone receptor domain

Domain Context

CATH Clusters

Superfamily	GPCR, family 2, extracellular hormone receptor domain
Functional Family	Corticotropin-releasing factor receptor 1

Enzyme Information

UniProtKB Entries (1)

CRFR1_HUMAN

Homo sapiens

Corticotropin-releasing factor receptor 1

PDB Structure

PDB	2L27
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	NMR structure of the first extracellular domain of corticotropin-releasing factor receptor 1 (ECD1-CRF-R1) complexed with a high affinity agonist. Grace, C.R., Perrin, M.H., Gulyas, J., Rivier, J.E., Vale, W.W., Riek, R. J.Biol.Chem.