CATH Domain 2knvB00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.10	DNA helicase RuvA subunit, C-terminal domain

Domain Context

CATH Clusters

Superfamily	DNA helicase RuvA subunit, C-terminal domain
Functional Family	Sequestosome 1

Enzyme Information

UniProtKB Entries (1)

SQSTM_HUMAN

Homo sapiens

Sequestosome-1

PDB Structure

PDB	2KNV
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-kappaB Signalling Long, J., Garner, T.P., Pandya, M.J., Craven, C.J., Chen, P., Shaw, B., Williamson, M.P., Layfield, R., Searle, M.S. J.Mol.Biol.