CATH Classification

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family 6-phosphogluconate dehydrogenase, decarboxylating

Enzyme Information

1.1.1.44
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating).
based on mapping to UniProt P96789
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.
-!- The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions. -!- Highly specific for NADP(+). -!- Cf. EC 1.1.1.343.

UniProtKB Entries (1)

P96789
6PGD_LACLM
Lactococcus lactis subsp. cremoris MG1363
6-phosphogluconate dehydrogenase, decarboxylating

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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