CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1010 | 5'-nuclease |
Domain Context
CATH Clusters
| Superfamily | 5'-nuclease |
| Functional Family |
Enzyme Information
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt P13319
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
| P13319 |
RNH_BPT4
Escherichia virus T4
Ribonuclease H
|
PDB Structure
| PDB | 2IHN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how FEN-1 family nucleases bind their substrates.
J.Biol.Chem.
|
