CATH Domain 2iceF01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.690	Alpha-macroglobulin, receptor-binding domain

Domain Context

CATH Clusters

Superfamily	Alpha-macroglobulin, receptor-binding domain
Functional Family	Complement C3

Enzyme Information

UniProtKB Entries (1)

CO3_HUMAN

Homo sapiens

Complement C3

PDB Structure

PDB	2ICE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Wiesmann, C., Katschke, K.J., Yin, J., Helmy, K.Y., Steffek, M., Fairbrother, W.J., McCallum, S.A., Embuscado, L., DeForge, L., Hass, P.E., van Lookeren Campagne, M. Nature