CATH Classification

Domain Context

CATH Clusters

Superfamily Pseudouridine synthase
Functional Family Pseudouridine synthase

Enzyme Information

5.4.99.29
23S rRNA pseudouridine(746) synthase.
based on mapping to UniProt P0AA37
23S rRNA uridine(746) = 23S rRNA pseudouridine(746).
-!- RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine(746). -!- The dual-specificity enzyme also catalyzes the formation of uridine(32) in tRNA. -!- Cf. EC 5.4.99.28.
5.4.99.28
tRNA pseudouridine(32) synthase.
based on mapping to UniProt P0AA37
tRNA uridine(32) = tRNA pseudouridine(32).
-!- The dual-specificity enzyme also catalyzes the formation of pseudouridine(746) in 23S rRNA. -!- Cf. EC 5.4.99.29.

UniProtKB Entries (1)

P0AA37
RLUA_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase A

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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