CATH Domain 2i7xA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Cleavage and polyadenylation specificity factor subunit 2

Enzyme Information

UniProtKB Entries (1)

CFT2_YEAST

Saccharomyces cerevisiae S288C

Cleavage factor two protein 2

PDB Structure

PDB	2I7X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Mandel, C.R., Kaneko, S., Zhang, H., Gebauer, D., Vethantham, V., Manley, J.L., Tong, L. Nature