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1 keywords

CATH Domain 2hhhG00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.455 Ribosomal Protein S7
Homologous Superfamily 1.10.455.10 Ribosomal protein S7 domain

Domain Context

CATH Clusters

Superfamily Ribosomal protein S7 domain
Functional Family 30S ribosomal protein S7

Enzyme Information

UniProtKB Entries (2)

Q5SJH3
RS16_THET8
Thermus thermophilus HB8
30S ribosomal protein S16
A0A0N0BLS5
RS17_THEAQ
Thermus aquaticus
30S ribosomal protein S17

PDB Structure

PDB 2HHH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Schluenzen, F., Takemoto, C., Wilson, D.N., Kaminishi, T., Harms, J.M., Hanawa-Suetsugu, K., Szaflarski, W., Kawazoe, M., Shirouzo, M., Nierhaus, K.H., Yokoyama, S., Fucini, P.
Nat.Struct.Mol.Biol.
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