CATH Domain 2hdmA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.50	OB fold (Dihydrolipoamide Acetyltransferase, E2P)
	2.40.50.40

Domain Context

CATH Clusters

Superfamily	2.40.50.40
Functional Family	Lymphotactin isoform X1

Enzyme Information

UniProtKB Entries (1)

XCL1_HUMAN

Homo sapiens

Lymphotactin

PDB Structure

PDB	2HDM
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity Tuinstra, R.L., Peterson, F.C., Elgin, E.S., Pelzek, A.J., Volkman, B.F. Biochemistry