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1 keywords

CATH Domain 2g97B02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

2.4.2.12
Nicotinamide phosphoribosyltransferase.
based on mapping to UniProt Q80Z29
Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho- alpha-D-ribose 1-diphosphate.

UniProtKB Entries (1)

Q80Z29
NAMPT_RAT
Rattus norvegicus
Nicotinamide phosphoribosyltransferase

PDB Structure

PDB 2G97
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866
Kim, M.-K., Lee, J.H., Kim, H., Park, S.J., Kim, S.H., Kang, G.B., Lee, Y.S., Kim, J.B., Kim, K.K., Suh, S.W., Eom, S.H.
J.Mol.Biol.
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