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1 keywords

CATH Domain 2g69A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q7SSI0
Q7SSI0_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 2G69
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mechanism of Drug Resistance Revealed by the Crystal Structure of the Unliganded HIV-1 Protease with F53L Mutation.
Liu, F., Kovalevsky, A.Y., Louis, J.M., Boross, P.I., Wang, Y.F., Harrison, R.W., Weber, I.T.
J.Mol.Biol.
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