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CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family Calcium/calmodulin-dependent protein kinase type II

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt O62305
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

O62305
KCC2D_CAEEL
Caenorhabditis elegans
Calcium/calmodulin-dependent protein kinase type II

PDB Structure

PDB 2F86
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.
Rosenberg, O.S., Deindl, S., Comolli, L.R., Hoelz, A., Downing, K.H., Nairn, A.C., Kuriyan, J.
Febs J.
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