CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.930 | BirA Bifunctional Protein; domain 2 |
|
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Bira Bifunctional Protein; Domain 2 |
| Functional Family |
Enzyme Information
| 6.3.4.15 |
Biotin--[biotin carboxyl-carrier protein] ligase.
based on mapping to UniProt Q59014
ATP + biotin + [biotin carboxyl-carrier protein]-L-lysine = AMP + diphosphate + [biotin carboxyl-carrier protein]-N(6)-biotinyl-L-lysine.
-!- The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC 6.3.4.14. -!- The carboxyl group is eventually transferred to acetyl-CoA by EC 2.1.3.15. -!- In some organisms the carrier protein is part of EC 6.4.1.2.
|
UniProtKB Entries (1)
| Q59014 |
BPL_METJA
Methanocaldococcus jannaschii DSM 2661
Putative biotin ligase
|
PDB Structure
| PDB | 2EJ9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure Of Biotin Protein Ligase From Methanococcus jannaschii
To be Published
|
