×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Dehydrogenase, chain A, domain 1
Functional Family

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q5KWX7
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q5KWX7
AROE_GEOKA
Geobacillus kaustophilus HTA426
Shikimate dehydrogenase (NADP(+))

PDB Structure

PDB 2EGG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Geobacillus kaustophilus
Bagautdinov, B., Kunishima, N.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...