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1 keywords

CATH Domain 2e2lE01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.60 4-Layer Sandwich
Topology 3.60.110 Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase
Homologous Superfamily 3.60.110.10 Carbon-nitrogen hydrolase

Domain Context

CATH Clusters

Superfamily Carbon-nitrogen hydrolase
Functional Family

Enzyme Information

3.5.1.49
Formamidase.
based on mapping to UniProt O25836
Formamide + H(2)O = formate + NH(3).
-!- Also acts, more slowly, on acetamide, propanamide and butanamide.

UniProtKB Entries (1)

O25836
AMIF_HELPY
Helicobacter pylori 26695
Formamidase

PDB Structure

PDB 2E2L
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
Hung, C.-L., Liu, J.-H., Chiu, W.-C., Huang, S.-W., Hwang, J.-K., Wang, W.-C.
J.Biol.Chem.
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